in the heart, others would place it intuitively in the brain, all would confine it to the soul; now in my opinion it resides primarily and principally in the nerves, and varies with their variations. Hence the difficulty of making the moral sense a universal guide of action, since it not only differs in many individuals, but in the same persons, at different periods of their existence, or (as I have often experienced) at different hours of the day. All this must depend upon the mobility of the nervous system; upon this may hinge the great difficulties which have puzzled metaphysicians respecting consciousness, identity, &c. If they had attended less to the nature of the soul, and more to the system of the nerves, they would have avoided innumerable errors, and probably would have made incalculably important discoveries. Nothing is wanting but some great German genius to bring this idea of a moral sense in the nerves into fashion. Indeed, if our friend Mad. *** would mention it in the notes to her new novel, it would introduce it in the most satisfactory manner possible to all the fashionable world abroad; and we take our notions in this country implicitly from the Continent. As for you, my dear Gabrielle, I know you cut the gordian knot at once, by referring, with your favourite moralist, every principle of human nature to self-love. This does not quite accord with my ideas; there is something harsh in it, that is repugnant to my sensibility; but you have a stronger mind than I have, and perhaps your theory is right. "You tell me I contradict myself continually," says the acute and witty Duke de la Rochefoucault: "No, but the human heart, of which I treat, is in perpetual contradiction to itself." Permit me to avail myself of this answer, dear Gabrielle, if you should accuse me of contradicting in this letter all that I said to you in my last. A few hours after I had despatched it the state of my nerves changed; I saw things of course in a new light, and repented having exposed myself to your raillery by writing in such a Magdalen strain. My nerves were more in fault than I. When one's mind or one's nerves grow weak, the early associations and old prejudices of the nursery recur, and tyrannize over one's reason: from this evil your liberal education and enviable temperament have preserved you; but have charity for my feminine weakness of frame, which too often counteracts the masculine strength of my soul. Now that I have deprecated your