indeed there are which are more potent than any counteracting causes to which they are commonly exposed; and accordingly there are some truths in medicine which are sufficiently proved by direct experiment. Of these the most familiar are those that relate to the efficacy of the substances known as Specifics for particular diseases, quinine, colchicum, lime-juice, cod-liver oil, and a few others. Even these are not invariably followed by success; but they succeed in so large a proportion of cases, and against such powerful obstacles, that their tendency to restore health in the disorders for which they are prescribed may be regarded as an experimental truth. If so little can be done by the experimental method to determine the conditions of an effect of many combined causes, in the case of medical science; still less is this method applicable to a class of phenomena more complicated than even those of physiology, the phenomena of politics and history. There, Plurality of Causes exists in almost boundless excess, and effects are, for the most part, inextricably interwoven with one another. To add to the embarrassment, most of the inquiries in political science relate to the production of effects of a most comprehensive description, such as the public wealth, public security, public morality, and the like: results liable to be affected directly or indirectly either in plus or in minus by nearly every fact which exists, or event which occurs, in human society. The vulgar notion, that the safe methods on political subjects are those of Baconian induction that the true guide is not general reasoning, but specific experience will one day be quoted as among the most unequivocal marks of a low state of the speculative faculties in any age in which it is accredited. Nothing can be more ludicrous than the sort of parodies on experimental reasoning which one is accustomed to meet with, not in popular discussion only, but in grave treatises, when the affairs of nations are the theme. How, it is asked, can an institution be bad, when the country has prospered under it? How can such or such causes have contributed to the prosperity of one country, when another has prospered without them? Whoever makes use of an argument of this kind, not intending to deceive, should be sent back to learn the elements of some one of the more easy physical sciences. Such reasoners ignore the fact of Plurality of Causes in the very case which affords the most signal example of it. So little could be concluded, in such a case, from any possible collation of individual instances, that even the impossibility, in social phenomena, of making artificial experiments